New evidence: Effects of Huntington’s disease mutation may begin in childhood

There is growing evidence to support the hypothesis that there is a neurodevelopmental component to the late-onset neurodegeneration occurring in the brain of huntingtin gene (HTT gene) mutation carriers, and that this increased susceptibility to brain cell death begins during childhood. Experts discuss the evidence that the HTT gene mutation affects brain and body growth […]

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A prognostic Alzheimer’s disease blood test in the symptom-free stage

Using a blood test, a German-Dutch research team has predicted the risk of Alzheimer’s disease in people who were clinically diagnosed as not having Alzheimer’s disease but who perceived themselves as cognitively impaired (Subjective Cognitive Declined, SCD). The researchers analyzed blood samples from an SCD cohort supervised at the Alzheimer Center Amsterdam. Using a test […]

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Long-term study finds dozens of new genetic markers associated with lifetime bone growth

A multidisciplinary team of researchers led by Children’s Hospital of Philadelphia (CHOP) has discovered several genetic markers associated with bone mineral accrual, which could ultimately help identify causes of eventual osteoporosis earlier in life through genetic testing. The findings, which were made possible by following a group of children over several years, were published online […]

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Mindfulness training does not reduce migraine frequency: study

Mindfulness-based stress reduction (MBSR) does not improve migraine frequency more than headache education, according to a study published online Dec. 14 in JAMA Internal Medicine. Rebecca Erwin Wells, M.D., M.P.H., from Wake Forest Baptist Health in Winston-Salem, North Carolina, and colleagues randomly assigned 89 adults (92 percent female) who experienced four to 20 migraine days […]

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Postpartum trajectory differs by race after hypertensive disorders of pregnancy

There are significant racial differences in postpartum blood pressure trajectories in women with hypertensive disorders of pregnancy, according to a study published online Dec. 22 in JAMA Network Open. Alisse Hauspurg, M.D., from the University of Pittsburgh School of Medicine, and colleagues assessed the racial differences in blood pressure trajectory in the first six weeks […]

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